Translational research & Preclinical
Rheomuco: A solution tailored to your needs
Translational research and preclinical research are fundamental steps of the drug discovery process. R&D pipelines are filled with a large number of new molecules and medical devices destined to treat patients and to improve their quality of life. Knowledge of drug or device activities is strategic to start building claims and to position the candidate in the large map of today’s drugs.
- Correctors and potentiators
- Gene therapy
- Nitric oxide
- Medical device
Some of these treatments fail in clinical trials debilitating resources, time and fracturing patients’ hopes.
Integrating Rheomuco in early clinical research
Rheomuco will offer additional information to the classical pharmacodynamics and pharmacokinetics data. If mucus rheology is used throughout the R&D process, it offers a better understanding of the disease characteristics as well as the therapeutic response including drug efficacy and clear analysis to support your decision-making on the next steps of your drug or device development.
The translational and preclinical studies have diverse purposes, mucus rheology can be used to fulfil the following objectives :
- Evaluation of a drug candidate in vitro by measuring the viscoelastic properties of mucus produced by cultured primary human cells
- Evaluation of a drug candidate ex vivo with human mucus
- Evaluation of a drug candidate ex vivo with animal models
Sample volume have always been an obstacle to using mucus rheology for pre-clinical studies. With Rheomuco, you can testing samples starting 20µL!
We are always open for a conversation about Rheomuco!