{"id":1494,"date":"2022-07-28T15:43:56","date_gmt":"2022-07-28T13:43:56","guid":{"rendered":"http:\/\/rheomuco.magali-tillocher.com\/?page_id=1494"},"modified":"2022-08-03T10:55:09","modified_gmt":"2022-08-03T08:55:09","slug":"recherche-translationnelle-preclinique","status":"publish","type":"page","link":"https:\/\/rheomuco.com\/fr\/recherche-translationnelle-preclinique\/","title":{"rendered":"Recherche translationnelle et pr\u00e9clinique"},"content":{"rendered":"\n[et_pb_section fb_built=\u00a0\u00bb1&Prime; custom_padding_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb module_id=\u00a0\u00bbtitle_std\u00a0\u00bb _builder_version=\u00a0\u00bb3.22&Prime; custom_padding_tablet=\u00a0\u00bb\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_4,3_4&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb module_id=\u00a0\u00bbbloc_title\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; width=\u00a0\u00bb100%\u00a0\u00bb max_width=\u00a0\u00bb100%\u00a0\u00bb custom_padding=\u00a0\u00bb0px||0px|\u00a0\u00bb use_custom_width=\u00a0\u00bbon\u00a0\u00bb width_unit=\u00a0\u00bboff\u00a0\u00bb custom_width_percent=\u00a0\u00bb100%\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_4&Prime; module_id=\u00a0\u00bbline_title\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb0px|0px|0px|0px\u00a0\u00bb custom_css_main_element=\u00a0\u00bbmax-height: 62px;\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][\/et_pb_column][et_pb_column type=\u00a0\u00bb3_4&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb0px|0px|0px|0px\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb0px|0px|0px|10px\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text admin_label=\u00a0\u00bbTitre de page\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; max_width=\u00a0\u00bb900px\u00a0\u00bb custom_css_main_element=\u00a0\u00bbborder:none;\u00a0\u00bb border_width_all=\u00a0\u00bb5px\u00a0\u00bb border_color_all=\u00a0\u00bb#3cb6b3&Prime;]<h1><span style=\"color: #008080\"><strong>Recherche translationnelle &amp; pr\u00e9clinique<\/strong><\/span><\/h1>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1&Prime; module_id=\u00a0\u00bbcontenu_std\u00a0\u00bb _builder_version=\u00a0\u00bb3.22&Prime; custom_padding=\u00a0\u00bb0px|1px|20px|\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb2_5,3_5&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; min_height=\u00a0\u00bb497.4px\u00a0\u00bb custom_padding=\u00a0\u00bb0px||0px|||\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb10px||0px|\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb][et_pb_column type=\u00a0\u00bb2_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_image src=\u00a0\u00bbhttps:\/\/rheomuco.com\/wp-content\/uploads\/2022\/07\/Photo-8_culture_cell_2.jpeg\u00a0\u00bb title_text=\u00a0\u00bbclose up of human cell culture technique\u00a0\u00bb show_bottom_space=\u00a0\u00bboff\u00a0\u00bb align_tablet=\u00a0\u00bbcenter\u00a0\u00bb align_phone=\u00a0\u00bb\u00a0\u00bb align_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb admin_label=\u00a0\u00bbImage Etape 1&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; transform_scale=\u00a0\u00bb120%|120%\u00a0\u00bb transform_translate=\u00a0\u00bb11px|-36px\u00a0\u00bb transform_translate_linked=\u00a0\u00bboff\u00a0\u00bb max_width=\u00a0\u00bb80%\u00a0\u00bb max_width_tablet=\u00a0\u00bb70%\u00a0\u00bb max_width_phone=\u00a0\u00bb\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb module_alignment=\u00a0\u00bbleft\u00a0\u00bb]&nbsp;\r[\/et_pb_image][\/et_pb_column][et_pb_column type=\u00a0\u00bb3_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text ul_item_indent=\u00a0\u00bb40px\u00a0\u00bb admin_label=\u00a0\u00bbEtape 1&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; header_2_font_size=\u00a0\u00bb18px\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; sticky_enabled=\u00a0\u00bb0&Prime;]<h2><strong>Rheomuco : une solution adapt\u00e9e \u00e0 vos besoins<br \/> <\/strong><\/h2>\n<p style=\"text-align: justify\">La recherche translationnelle et la recherche pr\u00e9clinique sont des \u00e9tapes fondamentales dans le processus de drug discovery. Les pipelines R&amp;D comportent de nombreuses mol\u00e9cules nouvelles et des dispositifs m\u00e9dicaux destin\u00e9s \u00e0 traiter des patients et \u00e0 am\u00e9liorer leur qualit\u00e9 de vie. La compr\u00e9hension des activit\u00e9s des m\u00e9dicaments ou des dispositifs est strat\u00e9gique pour commencer \u00e0 \u00e9tablir des revendications et \u00e0 positionner le candidat dans l\u2019espace des m\u00e9dicaments actuels.<\/p>\n<ul>\n<li>Bronchodilatateurs<\/li>\n<li>Corticost\u00e9ro\u00efdes<\/li>\n<li>Mucolytiques<\/li>\n<li>Antibiotiques<\/li>\n<li>Correcteurs et potentiateurs<\/li>\n<li>Th\u00e9rapies g\u00e9niques<\/li>\n<li>Monoxyde d\u2019azote<\/li>\n<li><a href=\"https:\/\/rheomuco.com\/fr\/validation-de-dispositifs-medicaux-pour-les-maladies-respiratoires\/\">Dispositifs m\u00e9dicaux<\/a><\/li>\n<\/ul>\n<h3>Certains traitements \u00e9chouent aux essais cliniques, gaspillant des ressources, du temps et brisant les espoirs de patients.<\/h3>\n<p><span style=\"font-weight: normal\">\u00a0<\/span><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00a0\u00bb3_5,2_5&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; custom_margin=\u00a0\u00bb-60px|auto|-60px|auto||\u00a0\u00bb custom_padding=\u00a0\u00bb0px||75px|||\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb0px||10px|\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb][et_pb_column type=\u00a0\u00bb3_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text ul_item_indent=\u00a0\u00bb40px\u00a0\u00bb admin_label=\u00a0\u00bbEtape 3&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; header_2_font_size=\u00a0\u00bb18px\u00a0\u00bb custom_margin=\u00a0\u00bb|||\u00a0\u00bb custom_padding=\u00a0\u00bb40px||30px|\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb0px||0px|\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; sticky_enabled=\u00a0\u00bb0&Prime;]<h2><strong><\/strong><strong>Int\u00e9gration de Rheomuco en recherche clinique pr\u00e9coce <\/strong><\/h2>\n<p style=\"text-align: justify\">Rheomuco vous fournira, d\u00e8s les premi\u00e8res \u00e9tapes cliniques, des informations compl\u00e9mentaires aux donn\u00e9es de pharmacodynamique classique et de pharmacocin\u00e9tique. Si la rh\u00e9ologie du mucus est utilis\u00e9e tout au long du processus de R&amp;D, elle permettra une meilleure compr\u00e9hension des caract\u00e9ristiques de la maladie ainsi que de la r\u00e9ponse th\u00e9rapeutique, incluant l\u2019efficacit\u00e9 du traitement, et une analyse claire en soutien au processus de d\u00e9cision concernant les \u00e9tapes suivantes de votre d\u00e9veloppement.<\/p>\n<p style=\"text-align: justify\">Les \u00e9tudes translationnelles et pr\u00e9cliniques ont des buts divers, la rh\u00e9ologie du mucus peut \u00eatre utilis\u00e9e pour remplir les objectifs suivants\u00a0:<\/p>\n<ul>\n<li style=\"text-align: justify\">\u00c9valuation d\u2019un candidat m\u00e9dicament <em>in vitro <\/em>par la mesure des propri\u00e9t\u00e9s visco\u00e9lastiques du <a href=\"https:\/\/rheomuco.com\/fr\/mucus-issu-de-cultures-cellulaires\/\"><span style=\"color: #008080\">mucus produit par des cultures cellulaires<\/span><\/a><\/li>\n<li style=\"text-align: justify\">\u00c9valuation d\u2019un candidat m\u00e9dicament <em>ex vivo<\/em> avec du <a href=\"https:\/\/rheomuco.com\/fr\/mucus-humain\/\"><span style=\"color: #008080\">mucus humain<\/span><\/a><\/li>\n<li style=\"text-align: justify\">\u00c9valuation d\u2019un candidat m\u00e9dicament <em>in vivo <\/em>avec des<a href=\"https:\/\/rheomuco.com\/fr\/mucus-de-modeles-animaux\/\"><span style=\"color: #008080\"> mod\u00e8les animaux<\/span><\/a><\/li>\n<\/ul>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb2_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_image src=\u00a0\u00bbhttps:\/\/rheomuco.com\/wp-content\/uploads\/2019\/12\/download-rheomuco-1.jpg\u00a0\u00bb title_text=\u00a0\u00bbdownload-rheomuco\u00a0\u00bb show_bottom_space=\u00a0\u00bboff\u00a0\u00bb align=\u00a0\u00bbright\u00a0\u00bb align_tablet=\u00a0\u00bbcenter\u00a0\u00bb align_phone=\u00a0\u00bb\u00a0\u00bb align_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb disabled_on=\u00a0\u00bbon|on|\u00a0\u00bb admin_label=\u00a0\u00bbImage Etape 2 (ordinateur only)\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; transform_scale=\u00a0\u00bb80%|80%\u00a0\u00bb max_width=\u00a0\u00bb80%\u00a0\u00bb max_width_tablet=\u00a0\u00bb70%\u00a0\u00bb max_width_phone=\u00a0\u00bb\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb]&nbsp;\r[\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00a0\u00bb1_5,3_5,1_5&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_5&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb][\/et_pb_column][et_pb_column type=\u00a0\u00bb3_5&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.7.0&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; sticky_enabled=\u00a0\u00bb0&Prime; custom_margin=\u00a0\u00bb||-4px|||\u00a0\u00bb]<h3 style=\"text-align: center\">Envie d\u2019\u00e9changer sur Rheomuco\u00a0? Nous sommes toujours partants !<\/h3>[\/et_pb_text][et_pb_text admin_label=\u00a0\u00bbbloc Download\u00a0\u00bb module_class=\u00a0\u00bbdownload\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; text_text_color=\u00a0\u00bb#ffffff\u00a0\u00bb text_font_size=\u00a0\u00bb13px\u00a0\u00bb text_orientation=\u00a0\u00bbcenter\u00a0\u00bb background_layout=\u00a0\u00bbdark\u00a0\u00bb max_width=\u00a0\u00bb25%\u00a0\u00bb max_width_tablet=\u00a0\u00bb\u00a0\u00bb max_width_phone=\u00a0\u00bb80%\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_padding=\u00a0\u00bb5px|5px|5px|5px\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; custom_css_main_element=\u00a0\u00bbbackground: #3bb6b3;\u00a0\u00bb border_radii=\u00a0\u00bbon|5px|5px|5px|5px\u00a0\u00bb saved_tabs=\u00a0\u00bball\u00a0\u00bb link_option_url=\u00a0\u00bbhttps:\/\/rheomuco.com\/fr\/contact\/\u00a0\u00bb sticky_enabled=\u00a0\u00bb0&Prime;]<p><a href=\"\/wp-content\/uploads\/2018\/01\/POSTER_ECFS.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><\/a>Contactez-nous!<\/p>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_5&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>Recherche translationnelle &amp; pr\u00e9clinique&nbsp; Rheomuco : une solution adapt\u00e9e \u00e0 vos besoins La recherche translationnelle et la recherche<a href=\"https:\/\/rheomuco.com\/fr\/recherche-translationnelle-preclinique\/\" rel=\"nofollow\" class=\"more\"> >> <\/a><\/p>\n","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1494","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/comments?post=1494"}],"version-history":[{"count":40,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1494\/revisions"}],"predecessor-version":[{"id":5906,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1494\/revisions\/5906"}],"wp:attachment":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/media?parent=1494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}