{"id":1232,"date":"2022-07-28T14:06:15","date_gmt":"2022-07-28T12:06:15","guid":{"rendered":"http:\/\/rheomuco.magali-tillocher.com\/?page_id=1232"},"modified":"2022-08-03T17:10:59","modified_gmt":"2022-08-03T15:10:59","slug":"mucus-de-modeles-animaux","status":"publish","type":"page","link":"https:\/\/rheomuco.com\/fr\/mucus-de-modeles-animaux\/","title":{"rendered":"Mucus de mod\u00e8les animaux"},"content":{"rendered":"\n[et_pb_section fb_built=\u00a0\u00bb1&Prime; custom_padding_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb module_id=\u00a0\u00bbtitle_std\u00a0\u00bb _builder_version=\u00a0\u00bb3.22&Prime; custom_padding_tablet=\u00a0\u00bb\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_4,3_4&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb module_id=\u00a0\u00bbbloc_title\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; background_size=\u00a0\u00bbinitial\u00a0\u00bb background_position=\u00a0\u00bbtop_left\u00a0\u00bb background_repeat=\u00a0\u00bbrepeat\u00a0\u00bb width=\u00a0\u00bb100%\u00a0\u00bb max_width=\u00a0\u00bb100%\u00a0\u00bb custom_padding=\u00a0\u00bb0px||0px|\u00a0\u00bb use_custom_width=\u00a0\u00bbon\u00a0\u00bb width_unit=\u00a0\u00bboff\u00a0\u00bb custom_width_percent=\u00a0\u00bb100%\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_4&Prime; module_id=\u00a0\u00bbline_title\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb0px|0px|0px|0px\u00a0\u00bb custom_css_main_element=\u00a0\u00bbmax-height: 62px;\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][\/et_pb_column][et_pb_column type=\u00a0\u00bb3_4&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb0px|0px|0px|0px\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb0px|0px|0px|10px\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text admin_label=\u00a0\u00bbTitre de page\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; max_width=\u00a0\u00bb900px\u00a0\u00bb custom_css_main_element=\u00a0\u00bbborder:none;\u00a0\u00bb border_width_all=\u00a0\u00bb5px\u00a0\u00bb border_color_all=\u00a0\u00bb#3cb6b3&Prime; border_style_all=\u00a0\u00bbsolid\u00a0\u00bb border_color=\u00a0\u00bb#3cb6b3&Prime; border_width=\u00a0\u00bb5px\u00a0\u00bb border_style=\u00a0\u00bbsolid\u00a0\u00bb]<h1><span style=\"color: #008080\"><strong>Mucus de mod\u00e8les animaux<\/strong><\/span><\/h1>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1&Prime; module_id=\u00a0\u00bbcontenu_std\u00a0\u00bb _builder_version=\u00a0\u00bb3.22&Prime; custom_padding=\u00a0\u00bb0px||20px|\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_2,1_2&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb _builder_version=\u00a0\u00bb3.25&Prime; custom_padding=\u00a0\u00bb0px||10px|\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb\u00a0\u00bb custom_padding_phone=\u00a0\u00bb\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_2&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_image src=\u00a0\u00bbhttps:\/\/rheomuco.com\/wp-content\/uploads\/2022\/07\/Photo-4_animal-testing-1.jpeg\u00a0\u00bb title_text=\u00a0\u00bbMany live garden snails under running water closeup. Washing sna\u00a0\u00bb align=\u00a0\u00bbcenter\u00a0\u00bb align_tablet=\u00a0\u00bbcenter\u00a0\u00bb align_phone=\u00a0\u00bb\u00a0\u00bb align_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb admin_label=\u00a0\u00bbVisuel 1&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; transform_scale=\u00a0\u00bb120%|120%\u00a0\u00bb max_width=\u00a0\u00bb65%\u00a0\u00bb max_width_phone=\u00a0\u00bb200px\u00a0\u00bb max_width_last_edited=\u00a0\u00bboff|phone\u00a0\u00bb]&nbsp;\r[\/et_pb_image][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_2&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text ul_item_indent=\u00a0\u00bb40px\u00a0\u00bb admin_label=\u00a0\u00bbBloc de texte 1&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime;]<h3 style=\"text-align: left\">De nombreux mod\u00e8les animaux sont couramment utilis\u00e9s en recherche fondamentale et dans les \u00e9tudes pr\u00e9cliniques pour la s\u00e9cr\u00e9tion de mucus\u00a0:<\/h3>\n<ul>\n<li>petits rongeurs\n<ul>\n<li>Rats<\/li>\n<li>Souris<\/li>\n<li>Furets<\/li>\n<\/ul>\n<\/li>\n<li>grands mammif\u00e8res\n<ul>\n<li>Chiens<\/li>\n<li>Moutons<\/li>\n<li>Chevaux<\/li>\n<li>Porcs<\/li>\n<\/ul>\n<\/li>\n<li>mod\u00e8les de mucus extracorporels\n<ul>\n<li>Escargots<\/li>\n<li>Myxines<\/li>\n<li>Limaces<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left\">[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00a0\u00bb1_5,3_5,1_5&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; custom_padding=\u00a0\u00bb10px||81px|||\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb0px||0px|\u00a0\u00bb custom_padding_phone=\u00a0\u00bb0px|||\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][\/et_pb_column][et_pb_column type=\u00a0\u00bb3_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][et_pb_text admin_label=\u00a0\u00bbBloc de texte 2&Prime; _builder_version=\u00a0\u00bb4.7.0&Prime; min_height=\u00a0\u00bb193.5px\u00a0\u00bb custom_margin=\u00a0\u00bb-3px||-98px|||\u00a0\u00bb custom_padding=\u00a0\u00bb0px||0px|||\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; sticky_enabled=\u00a0\u00bb0&Prime;]<p style=\"text-align: center\">Ces mod\u00e8les animaux peuvent \u00eatre tr\u00e8s utiles pour \u00e9tudier l\u2019impact fonctionnel d\u2019une alt\u00e9ration du mucus, tester des dispositifs m\u00e9dicaux ou encore \u00e9valuer l\u2019efficacit\u00e9 d\u2019un nouveau m\u00e9dicament. Les propri\u00e9t\u00e9s visco\u00e9lastiques du mucus sont essentielles pour vos <a href=\"https:\/\/rheomuco.com\/fr\/recherche-sur-le-mucus\/\"><span style=\"color: #008080\">projets de R&amp;D<\/span><\/a> ou <a href=\"https:\/\/rheomuco.com\/fr\/recherche-translationnelle-preclinique\/\"><span style=\"color: #008080\">pr\u00e9cliniques.<\/span><\/a><\/p>\n<h4 style=\"text-align: center\">Contactez-nous pour en savoir plus sur les propri\u00e9t\u00e9s visco\u00e9lastiques du mucus !<\/h4>\n[\/et_pb_text][et_pb_text admin_label=\u00a0\u00bbbloc Download\u00a0\u00bb module_class=\u00a0\u00bbdownload\u00a0\u00bb _builder_version=\u00a0\u00bb4.7.0&Prime; text_text_color=\u00a0\u00bb#ffffff\u00a0\u00bb text_font_size=\u00a0\u00bb13px\u00a0\u00bb text_orientation=\u00a0\u00bbcenter\u00a0\u00bb background_layout=\u00a0\u00bbdark\u00a0\u00bb max_width=\u00a0\u00bb25%\u00a0\u00bb max_width_tablet=\u00a0\u00bb\u00a0\u00bb max_width_phone=\u00a0\u00bb80%\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_padding=\u00a0\u00bb5px|5px|5px|5px\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; custom_css_main_element=\u00a0\u00bbbackground: #3bb6b3;\u00a0\u00bb border_radii=\u00a0\u00bbon|5px|5px|5px|5px\u00a0\u00bb saved_tabs=\u00a0\u00bball\u00a0\u00bb link_option_url=\u00a0\u00bbhttps:\/\/rheomuco.com\/fr\/contact\/\u00a0\u00bb sticky_enabled=\u00a0\u00bb0&Prime; custom_margin=\u00a0\u00bb42px|||||\u00a0\u00bb]<p>Contactez-nous !<\/p>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_5&Prime; _builder_version=\u00a0\u00bb3.25&Prime; background_position=\u00a0\u00bbtop_left\u00a0\u00bb custom_padding=\u00a0\u00bb|||\u00a0\u00bb custom_padding__hover=\u00a0\u00bb|||\u00a0\u00bb][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>Mucus de mod\u00e8les animaux&nbsp; De nombreux mod\u00e8les animaux sont couramment utilis\u00e9s en recherche fondamentale et dans les \u00e9tudes<a href=\"https:\/\/rheomuco.com\/fr\/mucus-de-modeles-animaux\/\" rel=\"nofollow\" class=\"more\"> >> <\/a><\/p>\n","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[et_pb_section bb_built=\"1\" module_id=\"title_std\" custom_padding_last_edited=\"on|desktop\" _builder_version=\"3.0.89\"][et_pb_row use_custom_width=\"on\" width_unit=\"off\" custom_width_percent=\"100%\" custom_padding=\"0px||0px|\" make_equal=\"on\" padding_top_1=\"0px\" padding_right_1=\"0px\" padding_bottom_1=\"0px\" padding_left_1=\"0px\" padding_top_2=\"0px\" padding_right_2=\"0px\" padding_bottom_2=\"0px\" padding_left_2=\"0px\" background_position_1=\"top_left\" background_position_2=\"top_left\" background_repeat_1=\"no-repeat\" background_repeat_2=\"no-repeat\" padding_2_tablet=\"0px|0px|0px|10px\" padding_2_last_edited=\"on|phone\" module_id_1=\"line_title\" custom_css_main_1=\"max-height: 62px;\" module_id=\"bloc_title\" _builder_version=\"3.0.73\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"1_4\"][\/et_pb_column][et_pb_column type=\"3_4\"][et_pb_text admin_label=\"Titre de page\" _builder_version=\"3.0.89\" border_width_all=\"5px\" border_color_all=\"#3cb6b3\" border_style_all=\"solid\" max_width=\"900px\" custom_css_main_element=\"border:none;\" border_color=\"#3cb6b3\" border_width=\"5px\" border_style=\"solid\"]<\/p><h1>Rheomuco, pour mieux comprendre les BPCO et valider les traitements en d\u00e9veloppement<\/h1><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=\"1\" module_id=\"contenu_std\" _builder_version=\"3.0.89\" custom_padding=\"0px||20px|\"][et_pb_row custom_padding=\"0px||10px|\" make_equal=\"on\" background_position_1=\"top_left\" background_position_2=\"top_left\" background_repeat_1=\"no-repeat\" background_repeat_2=\"no-repeat\" custom_padding_last_edited=\"on|phone\" _builder_version=\"3.0.98\"][et_pb_column type=\"1_2\"][et_pb_image admin_label=\"Visuel 1\" src=\"https:\/\/rheomuco.com\/wp-content\/uploads\/2018\/01\/1.3_BPCOcopd-CMYK.jpg\" align=\"center\" _builder_version=\"3.0.93\" max_width=\"65%\" max_width_phone=\"200px\" max_width_last_edited=\"off|phone\"]<br \/> [\/et_pb_image][\/et_pb_column][et_pb_column type=\"1_2\"][et_pb_text admin_label=\"Bloc de texte 1\" _builder_version=\"3.0.98\"]<\/p><p style=\"text-align: left;\"><a href=\"..\/..\/decouvrir-rheomuco\/\">Rheomuco<\/a> a pour vocation de quantifier et objectiver la <a href=\"..\/la-rheologie-des-secretions-pulmonaires\/\">visco\u00e9lasticit\u00e9<\/a> des s\u00e9cr\u00e9tions broncho-pulmonaires pour acqu\u00e9rir des connaissances nouvelles sur la BPCO, comprendre certains m\u00e9canismes de cette pathologie, ou encore identifier et valider de nouvelles th\u00e9rapies.<\/p><p style=\"text-align: left;\">La <strong>BPCO<\/strong>, Broncho-Pneumopathie Chronique Obstructive, est une maladie chronique inflammatoire touchant les poumons.<\/p><p style=\"text-align: left;\">Elle se caract\u00e9rise par une diminution du souffle li\u00e9e notamment \u00e0 l\u2019\u00e9paississement des bronches et des bronchioles par atrophie des muscles lisses et \u00e0 leur s\u00e9cr\u00e9tion plus importante de mucus.<\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding=\"10px||10px|\" custom_padding_phone=\"0px|||\" make_equal=\"on\" background_position_1=\"top_left\" background_position_2=\"top_left\" background_repeat_1=\"no-repeat\" background_repeat_2=\"no-repeat\" custom_padding_last_edited=\"on|tablet\" _builder_version=\"3.0.98\" custom_padding_tablet=\"0px||0px|\"][et_pb_column type=\"1_2\"][et_pb_text admin_label=\"Bloc de texte 2\" _builder_version=\"3.0.98\"]<\/p><p><a href=\"..\/..\/decouvrir-rheomuco\/\">Rheomuco<\/a>, instrument d\u00e9di\u00e9 \u00e0 la mesure de la visco\u00e9lasticit\u00e9 de ce mucus, a fait l'objet d\u2019une premi\u00e8re \u00e9tude clinique \u00ab\u00a0Assessment of Rheological Parameters of Human Sputum [Rheomuco, NCT02682290] au\u00a0<a href=\"http:\/\/www.chu-grenoble.fr\/\" target=\"_blank\" rel=\"noopener noreferrer\">CHU de\u00a0<\/a><a href=\"http:\/\/www.chu-grenoble.fr\/\" target=\"_blank\" rel=\"noopener noreferrer\">Grenoble-Alpes<\/a>. Les premiers r\u00e9sultats ont \u00e9t\u00e9 pr\u00e9sent\u00e9s en 2017 lors du congr\u00e8s international de l\u2019<a href=\"https:\/\/www.ersnet.org\">European Respiratory Society<\/a>.<br \/> L\u2019\u00e9tude a permis de discriminer les malades atteints de BPCO des volontaires sains et des asthmatiques, et de mesurer l\u2019impact d\u2019un traitement sur la visco\u00e9lasticit\u00e9 du mucus pulmonaire.<\/p><p>Un dispositif m\u00e9dical de diagnostic <em>in vitro<\/em> (DMDIV) est \u00e0 l\u2019\u00e9tude pour le diagnostic pr\u00e9coce et le suivi des malades atteints de BPCO.<\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_2\"][et_pb_image admin_label=\"Visuel 2\" src=\"https:\/\/rheomuco.com\/wp-content\/uploads\/2018\/01\/poster_ers.jpg\" url=\"\/wp-content\/uploads\/2018\/01\/POSTER_ERS.pdf\" url_new_window=\"on\" show_bottom_space=\"off\" align=\"center\" _builder_version=\"3.0.98\" max_width=\"240px\" max_width_tablet=\"200px\" max_width_phone=\"150px\" max_width_last_edited=\"on|tablet\" module_alignment=\"center\" custom_padding=\"0px|||\" custom_padding_phone=\"10px|||\" custom_padding_last_edited=\"on|desktop\" show_in_lightbox=\"off\" use_overlay=\"off\" always_center_on_mobile=\"on\" force_fullwidth=\"off\"]<br \/> [\/et_pb_image][et_pb_text admin_label=\"bloc Download\" background_layout=\"dark\" module_class=\"download\" _builder_version=\"3.0.98\" text_font_size=\"13px\" text_text_color=\"#ffffff\" border_radii=\"on|5px|5px|5px|5px\" text_orientation=\"center\" max_width=\"40%\" max_width_phone=\"70%\" max_width_last_edited=\"on|tablet\" module_alignment=\"center\" custom_padding=\"5px|5px|5px|5px\" custom_css_main_element=\"background: #3bb6b3;\" saved_tabs=\"all\"]<\/p><p><a href=\"\/wp-content\/uploads\/2018\/01\/POSTER_ERS.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">[icon name=icon_download]T\u00e9l\u00e9charger le poster ERS<\/a><\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","footnotes":""},"class_list":["post-1232","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/comments?post=1232"}],"version-history":[{"count":41,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1232\/revisions"}],"predecessor-version":[{"id":6064,"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/pages\/1232\/revisions\/6064"}],"wp:attachment":[{"href":"https:\/\/rheomuco.com\/fr\/wp-json\/wp\/v2\/media?parent=1232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}